Mighty mice hold key to muscle-wasting disease


By Rowan Hooper THANKS to research on “mighty mice”, the lives of people suffering from muscle-wasting diseases such as muscular dystrophy could be transformed. Two treatments that block a protein called myostatin, which slows muscle growth, are now in the pipeline. The first approach, announced this week, aims to use a drug to mop up myostatin. Meanwhile a second method, which is already in clinical trials in people with muscular dystrophy, uses antibodies to disable the protein. In 1997, researchers led by Se-Jin Lee of Johns Hopkins University School of Medicine in Baltimore, Maryland,
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